Study type: Epidemiological study (observational study)

Mobile phone use and risk of glioma in adults: case-control study. epidem.

Published in: BMJ 2006; 332 (7546): 883-887

Aim of study (acc. to author)

This population-based case-control study was conducted in five areas of the United Kingdom to investigate the risk of glioma in adults in relation to mobile phone use. The study is part of the INTERPHONE project.

Further details

Regular mobile phone use was defined as use for at least six months in the period more than a year before diagnosis.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Exposure groups

Group Description
Reference group 1 never use or less than six months one year before diagnosis
Group 2 regular use
Group 3 years since first use: 1.5 - 4
Group 4 years since first use: 5 - 9
Group 5 years since first use: ≥ 10
Group 6 lifetime years of use: 0.5 - 4
Group 7 lifetime years of use: 5 - 9
Group 8 lifetime years of use: ≥ 10
Group 9 cumulative hours of use: ≤ 99
Group 10 cumulative hours of use: 99 - ≤ 544
Group 11 cumulative hours of use: > 544
Group 12 cumulative number of calls: ≤ 2071
Group 13 cumulative number of calls: 2071 - ≤ 6909
Group 14 cumulative number of calls: > 6909
Group 15 cumulative hours of use ≥ 10 years ago: 0
Group 16 cumulative hours of use ≥ 10 years ago: ≤ 113
Group 17 cumulative hours of use ≥ 10 years ago: > 113
Group 18 proportion urban/rural at first use: mainly urban
Group 19 proportion urban/rural at first use: mainly rural
Group 20 proportion urban/rural at first use: both
Group 21 frequency of use in those with high grade tumors: non-regular
Group 22 frequency of use in those with high grade tumors: regular
Group 23 frequency of use in those with low grade tumors: non-regular
Group 24 frequency of use in those with low grade tumors: regular
Group 25 frequency of ipsilateral use: never/non-regular
Group 26 frequency of ipsilateral use: regular
Group 27 frequency of contralateral use: never/non-regular
Group 28 frequency of contralateral use: regular

Population

Case group

Control group

Study size

Cases Controls
Participants 966 1,716
Participation rate 51 % 45 %
Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

There was no relation for risk of glioma and use of mobile phone. An increased risk for tumour ipsilateral to side of phone use and a reduced risk for contralateral use was found which might be due to recall bias.

Limitations (acc. to author)

The observation period was only 10 years.

Study funded by

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