Study type: Medical/biological study (experimental study)

Amyotrophic Lateral Sclerosis (ALS) and extremely-low frequency (ELF) magnetic fields: A study in the SOD-1 transgenic mouse model. med./bio.

Published in: Amyotroph Lateral Scler 2009; 10 (5-6): 370-373

Aim of study (acc. to author)

A transgenic mouse model was used to assess the possible effect of extremely low frequency magnetic fields on the development of amyotrophic lateral sclerosis.

Background/further details

Seven mice per group were exposed to 50 Hz magnetic fields at two intensities before the onset of the clinical signs of amyotrophic lateral sclerosis.



Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 2 hr/day, 5 day/week for 7 weeks

Exposure 1

Main characteristics
Frequency 50 Hz
Exposure duration continuous for 2 hr/day, 5 day/week for 7 weeks
Exposure setup
Exposure source
Setup two sets of Merrit coils; mice placed in a 25 cm x 20 cm plastic cage in the center of the coil system; field uniform within 5 % inside the cage;
Sham exposure A sham exposure was conducted.
Measurand Value Type Method Mass Remarks
magnetic flux density 100 µT effective value measured - -
magnetic flux density 1,000 µT effective value measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The data did not reveal any evidence of a link between extremely low frequency exposure and amyotrophic lateral sclerosis in this transgenic mouse model.

Study character:

Study funded by

Related articles