Study type: Medical/biological study (experimental study)

Loss of bone calcium in exposure to 50 Hz magnetic fields. med./bio.

Published in: Electromagn Biol Med 2008; 27 (4): 402-408

Aim of study (acc. to author)

To investigate the effect of whole body exposure to electromagnetic fields on the calcium level of blood and bone in guinea pigs and the role of trace elements as protective agents on the induced effects of the exposure.

Background/further details

50 male guinea pigs were divided into four different exposure groups and one control group. The first group was sacrificed immediatly after the exposure, the second group was sacrificed 15 days after the end of exposure. The third group received after the exposure for 15 days a drug (centrum; to compensate for the lack of trace elements) and was then sacrificed. The fourth group received the drug during the exposure period and was sacrificed after the exposure.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 30 days

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 30 days
Exposure setup
Exposure source
Setup solenoids consisting of 270 turns of 2.2 mm insulated copper wire wound around a copper cylinder with an external diameter of 55 cm; rat's plastic cages placed in the center of the solenoids; temperature kept constant through water cooling
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.2 mT - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Blood analysis revealed significant increases in the blood calcium level in exposed animals compared to the control group, with the largest increase in the first group. Values of the bone calcium analysis revealed a significant decrease in bone calcium concentration in the first group compared to the control group and a slight repair in the calcium level in the second group. The administration of trace elements on the third and fourth group improved the bone condition compared to the first group. Blood calcium level was inversely proportional to bone calcium concentration.
The results indicate that the calcium has left the bone to the blood. The authors assume a compensatory effect of trace elements after the exposure and protective effects during the exposure.

Study character:

Study funded by

Related articles