To investigate the preventive effects of an electromagnetic field in osteoporosis occuring after ovariectomy (excision of one or both ovaries).
18 female rats (10 exposed, 8 sham exposed) were examined.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
50 Hz
Exposure duration:
repeated daily exposure, 4 h/day for 6 weeks
|
|
The animals were divided into two groups: the exposed (n=10) and non-exposed control (n= 8) groups.
| Frequency | 50 Hz |
|---|---|
| Type | |
| Waveform | |
| Exposure duration | repeated daily exposure, 4 h/day for 6 weeks |
| Exposure source | |
|---|---|
| Setup | The rats in the experimental group were housed individually in 24 x 25 x 28 cm³ methacrylate cages placed between two activated coils. The rats in the control group were housed similarly but between the inactive coils. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 1 mT | unspecified | measured | - | - |
The cortical thickness of the tibia was increased in exposed rats. The levels of sodium and potassium in the tibia of exposed rats were significantly increased as well.
Additionally an increased blood alkaline phosphatase level was observed after electromagnetic field exposure.
No significant differences in the levels of calcium, magnesium, lithium, or creatine were found.
These data support the hypothesis that an electromagnetic field may be an effective treatment method for osteoporosis.
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