Study type: Medical/biological study (experimental study)

Fifty-gigahertz microwave exposure effect of radiations on rat brain. med./bio.

Published in: Appl Biochem Biotechnol 2009; 158 (1): 126-139

Aim of study (acc. to author)

To study the effects of 50 GHz microwave exposure on the brain of male Wistar rats.

Background/further details

Six rats were exposed and six rats were sham exposed.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 GHz
Exposure duration: continuous for 2 hr/day on 45 days

Exposure 1

Main characteristics
Frequency 50 GHz
Type
Charakteristic
Exposure duration continuous for 2 hr/day on 45 days
Exposure setup
Exposure source
Setup rats placed in Plexiglas cages which were positioned halfway inside an anechoic chamber; chamber lined with radar-absorbing material with an attenuation of 40dB; horn antenna positioned in front of the cages
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 0.86 µW/cm² - measured - -
SAR 0.8 mW/kg - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed that the chronic exposure to these microwaves caused DNA double-strand breaks and a significant decrease in glutathione peroxidase and superoxide dismutase enzyme activities in brain cells, whereas catalase enzyme activity significantly increased in the brain samples of the exposed group compared with controls. Additionally, protein kinase C level significantly decreased in whole brain and hippocampus.
The authors conclude that prolonged exposure to 50 GHz microwave exposure may decrease the level of protein kinase C, cause DNA double-strand breaks and changes in antioxidant enzyme activities in the neurological system of male rats due to free radicals formation. The possible site of action of such irradiation seems to be the hippocampus.

Study character:

Study funded by

Related articles