Study type: Medical/biological study (experimental study)

Evaluation of genotoxic effects in male Wistar rats following microwave exposure. med./bio.

Published in: Indian J Exp Biol 2010; 48 (6): 586-592

Aim of study (acc. to author)

To study the effects of microwave exposure on micronuclei formation and antioxidant enzymatic system in adult male rats.

Background/further details

24 rats were divided into two different exposure groups and two different sham exposure groups (each group n=6).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 10 GHz
Exposure duration: continuous for 2 hr/day on 45 days
Exposure 2: 50 GHz
Exposure duration: continuous for 2 hr/day on 45 days

Exposure 1

Main characteristics
Frequency 10 GHz
Type
Charakteristic
Exposure duration continuous for 2 hr/day on 45 days
Exposure setup
Exposure source
Setup exposure cage placed in a chamber lined with RF absorbing material; E-field orientation parallel to the exposure cage
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 0.214 mW/cm² - - - -
SAR 0.014 W/kg - calculated - -

Exposure 2

Main characteristics
Frequency 50 GHz
Type
Charakteristic
Exposure duration continuous for 2 hr/day on 45 days
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 0.86 µW/cm² - - - -
SAR 0.8 mW/kg - calculated - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed that microwave exposure induced micronuclei formation and a significant increase in reactive oxygen species production (both more pronounced at 50 GHz). Significant changes in the enzyme activities of serum glutathione peroxidase (decrease), superoxide dismutase (decrease) and catalase (increase) were observed in exposed group as compared with control group.
The authors conclude that microwave exposure can be effective at genetic level.

Study character:

Study funded by

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