Study type: Medical/biological study (experimental study)

Single strand DNA breaks in rat brain cells exposed to microwave radiation. med./bio.

Published in: Mutation Research - Fundamental and Molecular Mechanism of Mutagenesis 2006; 596 (1-2): 76-80

Aim of study (acc. to author)

To investigate the effect of microwave exposure (2.45 and 16.5 GHz) on developing rat brain (35 days old).

Background/further details

Six rats per exposure and sham exposure condition were used (n=24).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: continuous for 2 hr/day on 35 days
Exposure 2: 16.5 GHz
Exposure duration: continuous for 2 hr/day on 35 days

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration continuous for 2 hr/day on 35 days
Exposure setup
Exposure source
Chamber wooden anechoic chamber lined on the inside with pyramidal shaped RF absorbing material
Setup 13 cm x 9.8 cm pyramidal horn antenna with the aperture in a distance of 2 d²/λ from the cages; six animal cages made of plexi glass placed inside the chamber in two piles so that 3 cages were put one above the other; six rats were exposed simultaneously
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 1 W/kg - - - -
power density 0.344 mW/cm² - measured - -

Exposure 2

Main characteristics
Frequency 16.5 GHz
Type
Exposure duration continuous for 2 hr/day on 35 days
Exposure setup
Exposure source
Setup 32 cm x 10 cm x 9 cm plexi glass cage for 2 animals which were exposed simultaneously; six rats were exposed
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2.01 W/kg - - - -
power density 1 mW/cm² - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed that the chronic exposure to 2.45 and 16.5 GHz under these experimental conditions caused a statistically significant increase in DNA single-strand breaks (increase in the length of DNA migration) in brain cells of rats.

Study character:

Study funded by

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