Study type: Medical/biological study (experimental study)

Detection of Low Level Microwave Radiation Induced Deoxyribonucleic Acid Damage Vis-a-vis Genotoxicity in Brain of Fischer Rats. med./bio.

Published in: Toxicol Int 2013; 20 (1): 19-24

Aim of study (acc. to author)

To examine the potential DNA damaging effects of microwave exposure in the brain of rats.

Background/further details

4 groups of rats were examined (n=6 per group): 1.) sham exposure, 2.) exposure to 900 MHz, 3.) exposure to 1800 MHz and 4.) exposure to 2450 MHz.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: 2 h/day, 5 days/week for 30 days
  • SAR: 0.5953 mW/kg
Exposure 2: 1,800 MHz
Exposure duration: 2 h/day, 5 days/week for 30 days
  • SAR: 0.5838 mW/kg
Exposure 3: 2,450 MHz
Exposure duration: 2 h/day, 5 days/week for 30 days
  • SAR: 0.6672 mW/kg

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration 2 h/day, 5 days/week for 30 days
Exposure setup
Exposure source
Distance between exposed object and exposure source 1 m
Chamber rats were restrained in a 30 cm Π5 cm Π20 cm (length x width x height) closed box divided into four compartments with holes of 1 cm diameter for ventilation, four rats per box, 2 boxes per exposure
Setup GTEM cell with outer dimensions of 220 cm x 120 cm x 80 cm (length x width x height); microwave chamber is lined with absorbers which minimize the possibility of any reflections; GTEM cell was placed in a temperature controlled room under constant lighting conditions
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.5953 mW/kg - calculated - -

Exposure 2

Main characteristics
Frequency 1,800 MHz
Type
Exposure duration 2 h/day, 5 days/week for 30 days
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.5838 mW/kg - calculated - -

Exposure 3

Main characteristics
Frequency 2,450 MHz
Type
Exposure duration 2 h/day, 5 days/week for 30 days
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.6672 mW/kg - calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In all exposure groups, a significant increase in DNA single-strand breaks was found in comparison to the control group.
The authors conclude that exposure to microwaves could have a DNA damaging effect in the brain of rats.

Study character:

Study funded by

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