Study type:
Epidemiological study
(observational study)
Distance from residence to power line and risk of childhood leukemia: a population-based case-control study in Denmark
epidem.
By:
Pedersen C, Raaschou-Nielsen O, Rod NH, Frei P, Poulsen AH, Johansen C, Schüz J
Published in: Cancer Causes Control 2014; 25 (2): 171-177
Aim of study (acc. to author)
Endpoint/type of risk estimation
Type of risk estimation:
(odds ratio (OR))
Exposure
Assessment
Exposure groups
|
Group
|
Description
|
|
Group 1
|
distance from address at birth to the nearest 132-400 kV power line: 0 - 199 m
|
|
Group 2
|
distance from address at birth to the nearest 132-400 kV power line: 200 - 599 m
|
|
Group 3
|
distance from address at birth to the nearest 132-400 kV power line: ≥ 600 m
|
Population
-
Group:
-
Age:
0–14 years
-
Observation period:
1968 - 2006
-
Study location:
Denmark
Case group
Control group
- not born in Denmark, not living in Denmark
-
Selection:
-
Matching:
- sex
- age
- case:control = 1:2
Study size
|
Cases |
Controls |
| Eligible |
1,698 |
3,396 |
Statistical analysis method:
- conditional logistic regression
(
adjustment:
)
Results (acc. to author)
Most of the addresses at birth (94.9 %) were located 600 m or more from the nearest 132-400 kV overhead power line. Of the 4,282 addresses at birth, for which both distance to the nearest power line had been calculated and the magnetic field strength estimated 12 addresses were exposed to ≥ 0.1 µT .
No higher risk of leukemia was found for children living 0-199 m (OR 0.76, CI 0.40-1.45) or for children living 200-599 m (OR 0.90, CI 0.66-1.22) compared to children who lived ≥ 600 m away from a 132-400 kV overhead power line. When restricting the analysis to 220 and 400 kV overhead power lines, slightly elevated risk was observed for children who lived 200-599 m from a power line was 1.76 (CI 0.82-3.77) compared to children who lived ≥ 600 m away. However, chance is a likely explanation for this finding as the result was not significant, numbers were small, and there were no indications of a higher risk closer to the lines since no cases were observed within 200 m of these.
Study funded by
-
CHILDREN with CANCER UK
-
Danish Cancer Society
-
Danish Energy Agency (Energistyrelsen)
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