Study type:
Medical/biological study
(experimental study)
The Cytome Assay as a Tool to Investigate the Possible Association Between Exposure to Extremely Low Frequency Magnetic Fields and an Increased Risk for Alzheimer's Disease
med./bio.
By:
Maes A, Anthonissen R, Wambacq S, Simons K, Verschaeve L
Published in: J Alzheimers Dis 2015; 50 (3): 741-749
The study comprised two parts. In the first part, cells were exposed to 10, 50, 100 and 500 µT magnetic fields. The second part was conducted as an independent repetition experiment with slightly changed exposure values, namely 5, 10, 50 and 100 µT. Each exposure was accompanied by its own unexposed control group and by a positive control (15 µg/ml methyl methane sulfonate).
a cylindrical coil (380 turn coil, 42 cm long, 20 cm inner diameter) with dimensions that were chosen so that it could be placed inside the incubator and provide a sufficiently large zone in which the cultures could be exposed to a nearly constant magnetic field (with a tolerance of a few percent)
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Effect of coexposure to 50 Hz magnetic fields and an aneugen on human lymphocytes, determined by the cytokinesis block micronucleus assay
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Can cytogenetics explain the possible association between exposure to extreme low-frequency magnetic fields and Alzheimer's disease?
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Chromosomal damage in human diploid fibroblasts by intermittent exposure to extremely low-frequency electromagnetic fields
Verheyen GR et al.
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Effect of coexposure to 50 Hz magnetic fields and an aneugen on human lymphocytes, determined by the cytokinesis block micronucleus assay
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Effects of 50 Hz EMF exposure on micronucleus formation and apoptosis in transformed and nontransformed human cell lines
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