The effects of exposure of rats to a 50 Hz magnetic field on the melatonin production of blood cells should be investigated.
It is assumed that melatonin is mainly secreted from the pineal gland and the effects of ELF-EMF on the production of melatonin from the pineal gland have been investigated during past decades. However, melatonin can also be produced by bone marrow and immune system cells in the blood.
Rats were divided into 2 groups (n=20 each): exposure group and control group.
Exposure duration: 2 hours/day for 3 months
|Exposure duration||2 hours/day for 3 months|
|Sham exposure||A sham exposure was conducted.|
|magnetic flux density||100 µT||-||-||-||-|
Exposure of rats to the magnetic field had no significant effect on melatonin levels in serum and whole blood samples compared to the control group.
However, melatonin levels in whole blood samples of both groups were about 2.5 times higher than in serum, indicating a noteworthy melatonin production in blood cells. That might challenge the historical assumption that the pineal gland is the main source of melatonin in vertebrates.
The authors conclude that exposure of rats to a 50 Hz magnetic field has no effect on the melatonin production of blood cells.