6-sulphatoxymelatonin is the major metabolite of melatonin and could easily non-invasive determined in excreted urine. 12 animals were used in this study (divided in to two groups/6 animals each). The groups were exposed to 100 µT and 50 µT flux density, respectively. After 2 weeks of acclimatisation to the light/dark cycle (12:12 h, light from 6.00 pm to 6.00 am) nocturnal urine was collected ad the end of the dark phase for four weeks. Animals were exposed to the magnetic field in the second week daily from 8.00 am to 4.00 pm.
Gobba F et al.
No association between occupational exposure to ELF magnetic field and urinary 6-sulfatoximelatonin in workers.
Davis S et al.
Effects of 60-Hz magnetic field exposure on nocturnal 6-sulfatoxymelatonin, estrogens, luteinizing hormone, and follicle-stimulating hormone in healthy reproductive-age women: results of a crossover trial.
Youngstedt SD et al.
No association of 6-sulfatoxymelatonin with in-bed 60-Hz magnetic field exposure or illumination level among older adults.
Noonan CW et al.
Relationship between amyloid beta protein and melatonin metabolite in a study of electric utility workers.
Heikkinen P et al.
Chronic exposure to 50-Hz magnetic fields or 900-MHz electromagnetic fields does not alter nocturnal 6-hydroxymelatonin sulfate secretion in CBA/S mice.
Bakos J et al.
Urinary 6-sulphatoxymelatonin excretion is increased in rats after 24 hours of exposure to vertical 50 Hz, 100 microT magnetic field.
Bakos J et al.
Sinusoidal 50 Hz, 500 microT magnetic field has no acute effect on urinary 6-sulphatoxymelatonin in Wistar rats.