6-sulphatoxymelatonin is the major metabolite of melatonin and can be determined easily non-invasively in excreted urine. A total of 20 adultrats were used (10 male and 10 female, divided into 2 groups: magnetic field-exposed (500 µT) and sham exposed (5 µT, stray field)). A light (9 h)/dark (15 h) cycle was maintained (light on at 7 a.m./light off at 4 p.m.). Urine was collected twice a day (i.e. at the end of the dark phase and light phase, respectively) over a period of 5 consecutive days. The magnetic field was turned on at 7 a.m. on day 3 and turned off at 7 a.m. on day 4 (total magnetic fieldexposure time 24 h).
Gobba F et al.
No association between occupational exposure to ELF magnetic field and urinary 6-sulfatoximelatonin in workers.
Davis S et al.
Effects of 60-Hz magnetic field exposure on nocturnal 6-sulfatoxymelatonin, estrogens, luteinizing hormone, and follicle-stimulating hormone in healthy reproductive-age women: results of a crossover trial.
Bakos J et al.
One week of exposure to 50 Hz, vertical magnetic field does not reduce urinary 6-sulphatoxymelatonin excretion of male wistar rats.
Heikkinen P et al.
Chronic exposure to 50-Hz magnetic fields or 900-MHz electromagnetic fields does not alter nocturnal 6-hydroxymelatonin sulfate secretion in CBA/S mice.
Bakos J et al.
Urinary 6-sulphatoxymelatonin excretion is increased in rats after 24 hours of exposure to vertical 50 Hz, 100 microT magnetic field.