Study type: Medical/biological study (experimental study)

Survival assessment of mouse preimplantation embryos after exposure to cell phone radiation. med./bio.

Published in: J Reprod Infertil 2016; 17 (3): 138-143

Aim of study (acc. to author)

The effects of exposure of mice 2-cell-state embryos to a 900-1800 MHz electromagnetic field on embryonal development and cell viability should be investigated.

Background/further details

40 mice were mated and on the following day, zygotes were isolated and incubated for 5 hours. Afterwards, 2-cell-state embryos were divided into 2 groups (n=150 each): exposure group and control group.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900–1,800 MHz
Exposure duration: 30 minutes/day for 4 days
  • SAR: 0.683 W/kg minimum
  • SAR: 0.725 W/kg maximum

Exposure 1

Main characteristics
Frequency 900–1,800 MHz
Type
Exposure duration 30 minutes/day for 4 days
Exposure setup
Exposure source
Chamber incubator with 37°C and 5% CO2
Setup "cell phone was held horizontally and parallel to the zygotes culture medium inside the incubator while the bottom of the phone being placed 1 cm above the upper from the stage of incubator" (?); phone was kept in talk mode and the distance between the phone and embryos was > 10 cm
Additional info embryos of the control group were kept in an incubator without exposure to the cell phone
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.683 W/kg minimum - - -
SAR 0.725 W/kg maximum - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

At the 2-cell stage, the percentage of dead embryos was significantly increased in the exposure group compared to the control group. Moreover, the rate of dead cells was significantly increased in blastocysts from the exposure group compared to the control group.
The embryonal survival rate at the blastocyst stage did not show significant differences between both groups.
The authors conclude that exposure of mice 2-cell-state embryos to a 900-1800 MHz electromagnetic field has no detrimental effects on embryonal development but might decrease cell viability.

Study character:

Study funded by

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