Study type: Medical/biological study (experimental study)

Lack of teratogenicity after combined exposure of pregnant mice to CDMA and WCDMA radiofrequency electromagnetic fields. med./bio.

Published in: Radiat Res 2009; 172 (5): 648-652

Aim of study (acc. to author)

To study the teratogenic effects of multi-signal radiofrequency electromagnetic fields on mouse fetuses.

Background/further details

Pregnant mice were divided into different groups: 1) sham exposed CDMA control mice, 2) CDMA-exposed mice, 3) sham exposed CDMA + WCDMA control mice and 4) CDMA + WCDMA simultaneously exposed mice. Mice received two 45 min radiofrequency field exposures, separated by a 15 minutes interval, daily throughout the entire gestation period. The mice were killed on the 18th day of gestation and fetuses were examined.
A relatively high SAR was used because if adverse effects in mice fetus were not detected at this SAR, realistic radiofrequency field exposures are unlikely to affect humans.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 848.5 MHz
Exposure duration: continuous 2 times 45 min/day, separated by 15 min, throughout gestation (17 days)
Exposure 2: 1,950 MHz
Exposure duration: 2 times 45 min/d, separated by 15 min, throughout gestation (17 days)

Exposure 1

Main characteristics
Frequency 848.5 MHz
Type
Exposure duration continuous 2 times 45 min/day, separated by 15 min, throughout gestation (17 days)
Additional info CDMA
Exposure setup
Exposure source
Chamber 2295 mm x 2293 mm x 1470 mm reverberation chamber
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 176.36 V/m effective value measured - 73.1 V/m - 176.36 V/m
SAR 4.04 W/kg average over mass calculated whole body 0.69 W/kg - 4.04 W/kg
SAR 2 W/kg average over mass calculated whole body at P = 30 W
power 60 W maximum - - -

Exposure 2

Main characteristics
Frequency 1,950 MHz
Type
Exposure duration 2 times 45 min/d, separated by 15 min, throughout gestation (17 days)
Additional info WCDMA
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 162.5 V/m effective value measured - 64.17 V/m - 162.5 V/m
SAR 7.13 W/kg average over mass calculated whole body 1.11 W/kg - 7.13 W/kg
SAR 2 W/kg average over mass calculated whole body at P = 18 W
power 60 W maximum - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • after exposure

Main outcome of study (acc. to author)

Simultaneous experimental exposure to CDMA and WCDMA radiofrequency electromagnetic fields did not cause any observable adverse effects on mouse fetuses.

Study character:

Study funded by

Related articles