To investigate the effect of 13 week magnetic field exposures on chemically induced breast cancer in rats.
DMBA (7,12-dimethylbenzanthracene) was used as chemical agent to induce breast cancer. Two sets of experiments were conducted, each including 100 rats, and differ only in the total amount of DMBA applied (20 mg and 8 mg respectively).
| Exposure | Parameters |
|---|---|
|
Exposure 1:
50 Hz
Exposure duration:
18.5 h/day, 7 days/week for 13 weeks
|
|
|
Exposure 2:
60 Hz
Exposure duration:
18.5 h/day, 7 days/week for 13 weeks
|
|
| Frequency | 50 Hz |
|---|---|
| Type | |
| Waveform | |
| Exposure duration | 18.5 h/day, 7 days/week for 13 weeks |
| Exposure source |
|
|---|---|
| Setup | coil sets consisting of four pairs of vertically oriented coils connected in series, stacked one above the other; to minimize stray fields the bottom and top pairs of coils produced magnetic fields in opposite directions |
| Sham exposure | A sham exposure was conducted. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 100 µT | - | - | - | - |
| magnetic flux density | 500 µT | - | - | - | - |
| Frequency | 60 Hz |
|---|---|
| Type | |
| Waveform | |
| Exposure duration | 18.5 h/day, 7 days/week for 13 weeks |
| Exposure source |
|
|---|---|
| Sham exposure | A sham exposure was conducted. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 100 µT | - | - | - | - |
No effect of magnetic field exposure on tumor size could be found. This study do not support the hypothesis that magnetic field exposure promotes breast cancer in this DMBA rat model.
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