Study type: Epidemiological study (observational study)

Handheld cellular telephone use and risk of brain cancer. epidem.

Published in: JAMA 2000; 284 (23): 3001-3007

Aim of study (acc. to author)

A hospital-based case-control study was conducted in the USA to investigate whether cellular telephone use is associated with brain cancer.

Further details

Use of a handheld cellular phone was defined as having a subscription to a cellular telephone service.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Exposure groups

Group Description
Reference group 1 cellular telephone use: 0 years
Group 2 cellular telephone use: 1 year
Group 3 cellular telephone use: 2-3 years
Group 4 cellular telephone use: ≥ 4 years
Reference group 5 cellular telephone use: 0 hours/month
Group 6 cellular telephone use: > 0 ≤ 0.72 hours/month
Group 7 cellular telephone use: > 0.72 ≤ 2.1 hours/month
Group 8 cellular telephone use: > 2.1 ≤ 10.1 hours/month
Group 9 cellular telephone use: > 10.1 hours/month
Reference group 10 cellular telephone use: 0 cumulative hours
Group 11 cellular telephone use: > 0 ≤ 8.7 cumulative hours
Group 12 cellular telephone use: > 8.7 ≤ 60 cumulative hours
Group 13 cellular telephone use: > 60 ≤ 480 cumulative hours
Group 14 cellular telephone use: > 480 cumulative hours

Population

Case group

Control group

Study size

Cases Controls
Eligible 571 -
Participants 469 422
Participation rate 82 % 90 %
Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

66 cases (14 %) and 76 controls (16 %) reported using cellular telephones. The mean duration of cellular telephone use was 2.8 years for cases and 2.7 years for controls. No increased risk for brain cancer was found among users of cellular telephones operating primarily on analog signals. The data suggested that the use of cellular telephones is not associated with the risk of brain tumors.

Limitations (acc. to author)

No conclusions can be drawn for long-term users.

Study funded by

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