Study type: Epidemiological study (observational study)

Mobile phone use and risk of acoustic neuroma: results of the Interphone case-control study in five North European countries. epidem.

Published in: Br J Cancer 2005; 93 (7): 842-848

Aim of study (acc. to author)

Six population-based case-control studies were conducted in Finland, Denmark, Sweden, Norway and UK to assess the risk of acoustic neuroma in relation to mobile phone use. They are part of the INTERPHONE study.

Further details

Regular use of a mobile phone was defined as having used a mobile phone for at least 6 months more to than 1 year prior diagnosis date.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Exposure groups

Group Description
Reference group 1 never or nonregular use
Group 2 regular use
Group 3 frequency of use not known
Group 4 years since first use: 1.5-4
Group 5 years since first use: 5-9
Group 6 years since first use: ≥10
Group 7 years since first use: not known
Group 8 lifetime years of use: 0.5-4
Group 9 lifetime years of use: 5-9
Group 10 lifetime years of use: ≥ 10
Group 11 lifetime years of use: not known
Group 12 cumulative number of calls: < 2149
Group 13 cumulative number of calls: 2149-8000
Group 14 cumulative number of calls: > 8000
Group 15 cumulative number of calls: not known
Group 16 cumulative hours of use: < 116
Group 17 cumulative hours of use: 116-534
Group 18 cumulative hours of use: > 534
Group 19 cumulative hours of use: not known
Group 20 cumulative hours of use by time since first use: < 10 years
Group 21 cumulative hours of use by time since first use: ≥ 10 years (< 90 hours)
Group 22 cumulative hours of use by time since first use: ≥ 10 years (≥ 90 hours)
Group 23 cumulative hours of use by time since first use: not known
Group 24 analogue phone use
Group 25 digital phone use
Group 26 ipsilateral side of tumor and phone use
Group 27 contralateral side of tumor and phone use

Population

Case group

Control group

Study size

Cases Controls
Eligible 827 8,460
Participants 678 3,553
Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

There was no increased risk of acoustic neuroma in relation to regular mobile phone use. No association of risk with duration of use, lifetime cumulative hours of use or number of calls, for analogue or digital phones separately was found. An increased risk after more than 10 years of use could not be ruled out.

Study funded by

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