Study type: Medical/biological study (experimental study)

The differential effects of 200, 591, and 2,450 MHz radiation on rat brain energy metabolism. med./bio.

Published in: Bioelectromagnetics 1984; 5 (4): 419-433

Aim of study (acc. to editor)

To measure three key compounds in brain energy metabolism during and after exposure to continuous wave (CW) radiofrequency radiation at three different frequencies and to develop a dose-response relationship for the effects.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 200 MHz
Modulation type: CW
Exposure duration: 2 min
-
Exposure 2: 591 MHz
Modulation type: CW
Exposure duration: 2 min
-
Exposure 3: 2.45 GHz
Modulation type: CW
Exposure duration: 2 min
-

Exposure 1

Main characteristics
Frequency 200 MHz
Type
Exposure duration 2 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Distance between exposed object and exposure source 0.015 m
Setup the head of the animals were held in teflon head holder so that the exposed brain was positioned directly below the upper-plate of microstrip system.
Additional info the microstrip consisted of two parallel plates.
Parameters

No parameters are specified for this exposure.

Exposure 2

Main characteristics
Frequency 591 MHz
Type
Exposure duration 2 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Distance between exposed object and exposure source 0.015 m
Setup the head of the animals were held in teflon head holder so that the exposed brain was positioned directly below the upper-plate of microstrip system.
Parameters

No parameters are specified for this exposure.

Exposure 3

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration 2 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Distance between exposed object and exposure source 0.015 m
Setup the head of the animals were held in teflon head holder so that the exposed brain was positioned directly below the upper-plate of microstrip system.
Parameters

No parameters are specified for this exposure.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Frequency-dependent alterations have been found for all three compounds. At 200 and 591 MHz, NADH fluorescence increased in a dose-dependent manner between approximately 1 and 10 mW/cm². Then it became constant at higher exposures. There was no effect at 2450 MHz. The ATP levels were decreased at 200 and 591 MHz but not at 2450 MHz. The creatine phosphate levels decreased only at 591 MHz. Temperature in the rat brain was essentially constant for all irradiations. A general mechanism for inhibition of the mitochondrial electron transport chain and creatine kinase reaction pathway by radiofrequency exposure has been proposed.

Study character:

Study funded by

Related articles