Study type: Medical/biological study (experimental study)

Effects of modulated microwave and X-ray irradiation on the activity and distribution of Ca2+-ATPase in small intestine epithelial cells med./bio.

Published in: Scanning Microsc 1994; 8 (3): 613-9
Journal partially peer-reviewed/peer-review process unclear

Aim of study (acc. to author)

To investigate the cellular distribution and activity of calcium-ATPase (Ca2+-ATPase) in murine small intestine epithelial cells by using electron microscopy after total body irradiation with AM-microwaves and X-ray, respectively (calcium-ATPase (Ca2+-ATPase) is a membrane spanning enzyme).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: AM
Exposure duration: continuous, 3 h

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Exposure duration continuous, 3 h
Modulation
Modulation type AM
Modulation frequency 16 Hz
Additional info

square-modulation

Exposure setup
Exposure source
  • not specified
Parameters
Measurand Value Type Method Mass Remarks
power density 10 W/m² maximum - - 0,1; 0,5; 1 mW/cm²

Reference articles

  • Somosy Z et al. (1993): Effects of modulated and continuous microwave irradiation on pyroantimonate precipitable calcium content in junctional complex of mouse small intestine

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The microwave irradiation leads to a decrease of enzyme activity on the lateral membrane regions. A similar decrease was induced by X-ray irradiation. After X-ray irradiation of 1 Gy the enzyme activity was restored within 24 hours, whereas a X-ray irradiation of 5 Gy leads to a decreased activation persisting up to 24 hours.

Study character:

Study funded by

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