|Pulse width||5 µs|
|Repetition frequency||330 Hz|
The results indicate that the exposure of the cells influenced the monocyte-dependent immunoregulatory mechanisms responsible for the initiation of immune response. The exposure further significantly increased the production of IL-1 and decreased the production of IL-1ra. The changed ratio of IL-1/IL-1ra resulted in an increased value of lymphocyte-monocyte cooperation index, which reflects the activation of immunogenic and proinflammatory functions of monocytes. The proliferative response of T lymphocytes to mitogens (PHA, concanavalin A) was not changed. But the exposure significantly increased the production of IL-10, the immunoregulatory lymphokine that is involved in the T cell-monocyte interaction. The immunstimulatory effects of the 1300 MHz fields seem to affect preferentially the immunogenic functions of monocytes and the increased production of IL-10 seems to be a secondary reaction of T cells in response to activated monocytes.