Study type:
Medical/biological study
(experimental study)
In utero and early-life exposure of rats to a Wi-Fi signal: Screening of immune markers in sera and gestational outcome
med./bio.
By:
Ait-Aissa S, Billaudel B, Poulletier de Gannes F, Ruffie G, Duleu S, Hurtier A, Haro E, Taxile M, Athane A, Geffard M, Wu T, Wiart J, Bodet D, Veyret B, Lagroye I
Published in: Bioelectromagnetics 2012; 33 (5): 410-420
The period of exposure (from the 6thgestational day to 5 weeks postnatal) covered development of the immune system mainly occurring in utero and its maturation postnatal. Pregnantrats were exposed at different specific absorption rates (each exposure condition 10-12 rats). Dams were exposed from days 6 to 21 of gestation and together with three newborns (two males, one female) per litter from birth until weaning (postnatal day 21). Then, dams were removed and the three pups were exposed from day 21 until postanatal day 35. On day 35 after birth, all pups were sacrificed and sera collected. One male per litter was used to obtain serum samples (sham exposure group: n=10; 0.08 W/kg group: n=10; 0.4 W/kg group: n=12; 4 W/kg group: n=9 and cage control: n=11). Positive controls were performed by using an arthritis rat model using Mycobacterium tuberculosis H37RA in male Wistar rats (n=3).
cubic reverberation chamber (150 cm x 150 cm x 150 cm) with six antennas, respectively one in the middle of each side of the cube
Setup
the six antennas were activated at random; three stirrers used for mode mixing to obtain symmetrical and uniform exposure; WiFi-signal was amplified by a 70 W power amplifier to reach the different SAR values
Under these experimental conditions, whole-body in utero and extended postnatalexposure of rats to a WiFisignal at SAR levels up to 4 W/kg for the dams and transiently up to 9 W/kg for the pups had no detectable effects on the production of immunoglobulins directed against the selected antigens related to several pathological processes or on the gestational outcome (i.e. number of pups per litter, body weights of pups).
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