Study type: Medical/biological study (experimental study)

Influence of electromagnetic fields and protective effect of CAPE on bone mineral density in rats. med./bio.

Published in: Arch Med Res 2006; 37 (7): 818-821

Aim of study (acc. to author)

To study the effects of the irradiation emitted by mobile phones on bone mineral density of rats.

Background/further details

The effects of caffeic acid phenethyl ester (CAPE) on the allegedly irradiation-induced changes were also evaluated. CAPE is one of the major components of honeybee propolis. It has been used in folk medicine for many years in Middle East countries. CAPE was found to be a potent free radical scavenger and antioxidant.
48 rats were divided into five groups: 1) control, 2) exposed to 900 MHz, 3) exposed to 900 MHz and CAPE treatment, 4) exposed to 1800 MHz, 5) exposed to 1800 MHz and CAPE treatment.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: CW
Exposure duration: repeated daily exposure, 30 min/day, 5 days/week, for 4 weeks
Exposure 2: 1,800 MHz
Modulation type: CW
Exposure duration: repeated daily exposure, 30 min/day, 5 days/week, for 4 weeks

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration repeated daily exposure, 30 min/day, 5 days/week, for 4 weeks
Modulation
Modulation type CW
Exposure setup
Exposure source
Setup The exposure system consisted of a ventilated round plastic tube cage (12 cm long, 5.5 cm in diameter) and a half-wave dipole antenna. The whole body of the rat was positioned in close contact above the antenna.
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 1 mW/cm² mean measured - ± 0.4 mW/cm²
SAR 2 W/kg peak value unspecified - -

Exposure 2

Main characteristics
Frequency 1,800 MHz
Type
Exposure duration repeated daily exposure, 30 min/day, 5 days/week, for 4 weeks
Modulation
Modulation type CW
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
power density 1 mW/cm² mean measured - ± 0.4 mW/cm²
SAR 2 W/kg peak value unspecified - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Bone mineral densities were decreased in the exposed groups and increased in the CAPE treatment groups, but the changes were not significant.

Study character:

Study funded by

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