The study examined the effects of continuous wave or GSM modulated radiofrequency exposure on cellular ornithine decarboxylase enzyme activity in fibroblasts, two neural cell lines and primary astrocytes at higher exposure levels (SAR levels of 1.5, 2.5, and 6.0 W/kg) as in a previous study (publication 14027).
Medium change and serum deprivation was used as positive control.
| Frequency | 872 MHz |
|---|---|
| Type | |
| Charakteristic |
|
| Exposure duration | continuous for 2, 8, or 24 h |
| Exposure source | |
|---|---|
| Chamber | Exposures were carried out in a temperature controlled waveguide exposure system described earlier together with dosimetric details [Hoyto et al., 2006]. |
| Setup | Approximately 20 h prior to exposure, cells were seeded into four 55-mm glass Petri dishes two of which were later placed in the exposure chamber and the other two in the sham-exposure chamber. |
| Sham exposure | A sham exposure was conducted. |
| Additional info | Some of the initial experiments were carried out with a slight temperature difference between the exposure and sham-exposure chambers (max. 0.8°C lower in the latter), due to an improperly functioning temperature sensor. Sham-sham experiments were carried out to check possible differences between the exposure chambers. |
| Frequency | 872 MHz |
|---|---|
| Type | |
| Charakteristic |
|
| Exposure duration | continuous for 2, 8, or 24 h |
| Modulation type | CW |
|---|
| Exposure source |
|
|---|---|
| Sham exposure | A sham exposure was conducted. |
Ornithine decarboxylase enzyme activity was significantly decreased by radiofrequency exposure in primary cells, but the secondary cells (cell lines) showed essentially no response to similar radiofrequency exposure. This is a very interesting result, because function of the primary cells is closer to normal tissues than that of secondary transformed cell lines. In contrast to some previous studies (see "related articles"), no differences between the modulated and continuous wave signals were found.
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