Eighteen tricolour guinea pigs (nine males and nine females) were used, six in the control group and 12 in the exposure group. The animals were shaved before exposure. Punch biopsies of the skin were taken within 48 to 72 hours following each session, and 2 months following the final treatment.
|Pulse width||3 ms|
No parameters are specified for this exposure.
A slight erythema accompanied by an increase in local temperature (between 3 and 5 °C) was found after each exposure. The most relevant changes were seen in the papillary region of the dermis which underwent an expansion due to oedema and congestion in the first half of the experiment. An increase in cellularity and the accumulation of intercellular substance followed. Likewise, the content of collagen, elastic fibres and mucopolysaccharides increased.