Study type: Medical/biological study (experimental study)

Effect of GSM-900 and -1800 signals on the skin of hairless rats. I: 2-hour acute exposures. med./bio.

Published in: Int J Radiat Biol 2006; 82 (9): 669-674

Aim of study (acc. to author)

To study whether the cells of hairless rat skin are affected by acute local exposure to GSM-900 or -1800 radiofrequency irradiation.

Background/further details

To perform positive controls rats were exposed to UV-B radiation.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 2 h
  • SAR: 5.8 W/kg mean (± 0.4 W/kg at 1 mm depth)
Exposure 2: 1,800 MHz
Modulation type: pulsed
Exposure duration: continuous for 2 h
  • SAR: 4.8 W/kg mean (± 0.4 W/kg at 1 mm depth)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 2 h
Modulation
Modulation type pulsed
Exposure setup
Exposure source
  • square loop antenna (1 cm x 3 cm)
Setup Animals were restrained in rocket type plastic tubes and exposed using a loop antenna [Leveque et al., 2004] located on the right side of the back.
Sham exposure A sham exposure was conducted.
Additional info For positive control, two rats were exposed to UVB irradiation (400 mJ/cm²).
Parameters
Measurand Value Type Method Mass Remarks
SAR 5.8 W/kg mean estimated - ± 0.4 W/kg at 1 mm depth

Exposure 2

Main characteristics
Frequency 1,800 MHz
Type
Exposure duration continuous for 2 h
Modulation
Modulation type pulsed
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 4.8 W/kg mean estimated - ± 0.4 W/kg at 1 mm depth

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No major histological alterations were found in the studied cellular parameters immediately after the 2 h local exposure to GSM-900- or -1800. No difference in epidermis thickness was detected among the animal groups. Radiofrequency exposure did not affect cell proliferation. Filaggrin, collagen, and elastin were not modified by exposure to GSM-900 or -1800 signals.

Study character:

Study funded by

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