Study type: Medical/biological study (experimental study)

Effect of ELF electric field on some on biochemistry characters in the rat serum. med./bio.

Published in: Toxicol Ind Health 2011; 27 (4): 329-333

Aim of study (acc. to author)

To study the possible effects of 50 Hz electric fields on plasma total cholesterol and triglyceride concentration in male rats after short- and long-term electric field exposure.

Background/further details

60 rats were divided into three groups (each n=20): control group, exposure group for 10 days and exposure group for 30 days.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: one hour daily for 10 days or 30 days

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration one hour daily for 10 days or 30 days
Exposure setup
Exposure source
  • parallel plates
Setup 2 mm thick zinc-plated tin sheets 50 cm x 100 cm placed upright on polyvinyl chloride stands parallel to each other in a distance of 50 cm; three plastic cages with the rats placed between the plates; cages for sham exposure placed in another room during exposure
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 10 kV/m - calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Total cholesterol concentration in the plasma of the two exposure groups decreased significantly when compared with the control group. Plasma triglyceride levels showed similar changes.
In conclusion, 50 Hz electric fields may significantly decrease plasma total cholesterol and triglyceride levels in rodents, especially with long-term exposure.

Study character:

Study funded by

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