Study type: Medical/biological study (experimental study)

Electric field effects on Guinea pig serum: the role of free radicals. med./bio.

Published in: Electromagn Biol Med 2007; 26 (3): 207-223

Aim of study (acc. to author)

To study the effects of extremely low frequency electric field exposure on production of free radicals in guinea pigs.

Background/further details

A total of 280 guinea pigs were divided into 14 groups (each group n = 20) , and each group was subjected to various combinations of electric field intensities and directions. Twenty guinea pigs were used as sham exposed controls.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 8 h per day over 3 days (in horizontal or vertical field, respectively)

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 8 h per day over 3 days (in horizontal or vertical field, respectively)
Exposure setup
Exposure source
Setup wooden cages with dimensions of 80 cm x 80 cm x 18 cm; copper plates mounted on top and bottom face of cage for vertical field, on left and right for horizontal field
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 1.8 kV/m maximum measured and calculated - field strengths 0.3; 0.6; 0.8; 1; 1.35; 1.5 and 1.8 kV/m

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Vertical and horizontal application of extremely low frequency electric fields in the range of 1.35, 1.5, and 1.8 kV/m increased TBARS levels and superoxide dismutase enzyme activity as compared to the controls and to applied electric fields of 0.3, 0.6, 0.8, and 1 kV/m. Serum levels of the other biochemical parameters were not statistically significant.

Study character:

Study funded by

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