Study type: Medical/biological study (experimental study)

Effects of alternating magnetic field on the metabolism of the healthy and diabetic organisms. med./bio.

Published in: Braz. arch. biol. technol. 2004; 47 (5): 523-530

Aim of study (acc. to author)

The effects of a chronic exposure of healthy and diabetic rats to 50 Hz magnetic fields on metabolic and hematologic parameters should be investigated.

Background/further details

Diabetes in diabetic rats was generated by an injection of streptozotocin. 80 rats were divided into the following groups (sizes of groups not stated): 1) healthy rats, sham exposure for group 2, 2) healthy rats, exposure to 5 mT magnetic field, 3) healthy rats, sham exposure for group 4, 4) healthy rats, exposure to 8 mT magnetic field, 5) diabetic rats, sham exposure for group 6, 6) diabetic rats, exposure to 5 mT magnetic field.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 165 min/day for 3 weeks
Exposure 2: 50 Hz
Exposure duration: continuous for 165 min/day for 3 weeks

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 165 min/day for 3 weeks
Exposure setup
Exposure source
Chamber 8 animals were kept in a plexiglas cage during exposure; rats were kept in seven separate, stainless steel cages
Setup plexiglas cage was placed in north-south oriented magnetic field, temperature of solenoid was always kept between 21-24°C
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 5 mT - - - groups 2 and 6

Exposure 2

Main characteristics
Frequency 50 Hz
Exposure duration continuous for 165 min/day for 3 weeks
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 8 mT - - - group 4

Reference articles

  • Öcal I et al. (2004): The effects of chronic AC magnetic field on contraction and relaxation of isolated thoracic aorta rings of healthy and diabetic rats.
  • Itegin M et al. (1995): Effects of static magnetic field on specific adenosine-5'- triphosphatase activities and bioelectrical and biomechanical properties in the rat diaphragm muscle.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

An increase in body weight was found in all groups with healthy animals (1-4) whereas diabetic groups (5 and 6) showed a loss of weight. Total cholesterol was significantly decreased in group 6 (exposed) compared to group 5, the level of triglycerides as well as the level of glucose were significantly decreased in group 2 (exposed) compared to group 1 and in group 6 (exposed) compared to group 5. No results were displayed for groups 3 and 4 (note from the EMF-Portal editorial office).
The authors conclude, that a chronic exposure of healthy and diabetic rats to the tested 50 Hz magnetic fields has a depressing effect on their metabolism .

Study character:

Study funded by

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