Study type: Medical/biological study (experimental study)

Acute exposure to 50-Hz magnetic fields increases interleukin-6 in young healthy men. med./bio.

Published in: J Clin Immunol 2011; 31 (6): 1105-1111

Aim of study (acc. to author)

To study the effects of acute exposure to 50 Hz magnetic fields on the production of different interleukins in humans.

Background/further details

32 young men (20-30 years old) were divided into one sham exposed and one exposed group (each group n=16). The subjects were exposed to the magnetic field from 23:00 to 8:00 and blood samples were collected during each session at different time points (11:00, 17:00, 22:00, 01:00, 04:00, 06:00, and 08:00). Before the two experimental sessions there was a session for acclimatization (two weeks before the first experimental session; without exposure).



Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 9 h (session 1) or intermittend for 9 h : 1 h on - 1 h off (session 2)

Exposure 1

Main characteristics
Frequency 50 Hz
Exposure duration continuous for 9 h (session 1) or intermittend for 9 h : 1 h on - 1 h off (session 2)
Exposure setup
Exposure source
Setup two persons exposed in the same room lying in wooden beds arranged parallel to each other; rooms for exposure and sham exposure 7 m apart; three 120 cm x 140 cm rectangular Helmholtz coils, spaced 80 cm apart, positioned at the level of the head, groin and ankles at each bed; coils wrapped in wood
Sham exposure A sham exposure was conducted.
Additional info whenever the exposure source was turned "on", the magnetic field was on a 15 s "on-off" cycle
Measurand Value Type Method Mass Remarks
magnetic flux density 10 µT - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • during exposure

Main outcome of study (acc. to author)

The data showed that an intermittent exposure to 50 Hz magnetic fields significantly increased IL-6 production (at 6:00 and 8:00). However, no effects were found on interleukin IL-1beta, IL-2, IL-1RA, and IL-2R.

Study character:

Study funded by

Related articles