To assess glial fibrillary acidic protein (GFAP) levels in the brain of six week-old and twelve month-old rats, after exposure to GSM 900 MHz. Also interleukin expression and plasma levels of corticosterone and the emotional memory were examined.
For both ages rats were randomly assigned to either an exposure group or a sham exposure group (n=8-9 per group). On the first day of the experiment the rats were subjected to a fear conditioning training. After 48 hours they were exposed to an GSM signal for 15 minutes and tested for the sound memory. After additional 48 hours, contextual memory was tested and immediately followed by sacrifice.
Additionally, twelve control groups (n=6 per group) with six week-old rats were assigned which were sacrificed 30 minutes, 5 hours or 24 hours following (a) daily handling (cage control), (b) a single, 15 minutes, 6 W/kg exposure, (c) a single, 15 minutes sham exposure or (d) a 15 minutes sham exposure followed by a fear conditioning session.
|Exposure duration||continuous for 15 min|
|Duty cycle||12.5 %|
|Repetition frequency||217 Hz|
Acute GSM 900 MHz exposure did not alter the level of glial fibrillary acidic protein in the brain of rats.
An increase in IL-1ß in the olfactory bulb in exposed 12 month-old rats was found in comparison to 6 week-old rats and sham exposed ones. Additionally, an increased corticosterone level in 6 week-old exposed rats and an enhanced emotional memory in 12 month-old exposed rats was found in comparison to sham exposed rats.
The authors concluded that the data showed an age-dependent response to GSM exposure in neuro-immunity, stress and behavioural parameters.