Study type: Medical/biological study (experimental study)

Histopathological examinations of rat brains after long-term exposure to GSM-900 mobile phone radiation. med./bio.

Published in: Brain Res Bull 2008; 77 (5): 257-263

Aim of study (acc. to author)

To study the histopathological effects of repeated exposures for a long period to GSM-900 irradiation on rat brains.

Background/further details

A total of 56 rats was divided into three groups: 1) exposure groups (n=32): 16 animals per exposure group, 2) sham exposure group (n=16) and 3) cage control group (n=8). Five to seven weeks after the last exposure (during this time interval the memory tests were performed), the animals, at an age of 18-20 months, were anaesthetized and killed.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: 2 hr/week for 55 weeks
  • SAR: 0.6 mW/kg average over mass (whole body)
  • SAR: 60 mW/kg average over mass (whole body)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Waveform
Exposure duration 2 hr/week for 55 weeks
Exposure setup
Exposure source
Setup TEM cell connected to a GSM mobile phone; rats placed in 14 cm x 14 cm x 7 cm plastic trays in the TEM cell
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.6 mW/kg average over mass - whole body -
SAR 60 mW/kg average over mass - whole body -

Reference articles

  • Nittby H et al. (2008): Cognitive impairment in rats after long-term exposure to GSM-900 mobile phone radiation.
  • Belyaev IY et al. (2006): Exposure of rat brain to 915 MHz GSM microwaves induces changes in gene expression but not double stranded DNA breaks or effects on chromatin conformation.
  • Salford LG et al. (2003): Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones.
  • Persson BRR et al. (1997): Blood-brain barrier permeability in rats exposed to electromagnetic fields used in wireless communication.
  • Salford LG et al. (1994): Permeability of the blood-brain barrier induced by 915 MHz electromagnetic radiation, continuous wave and modulated at 8, 16, 50, and 200 Hz.
  • Salford LG et al. (1993): Permeability of the blood-brain barrier induced by 915 MHz electromagnetic radiation, continuous wave and modulated at 8, 16, 50 and 200 Hz.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No significant alteration of any of these histopathological parameters was found, when comparing the GSM exposed animals to the sham exposed controls.

Study character:

Study funded by

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