研究のタイプ: 医学/生物学の研究 (experimental study)

[フィッシャーラット脳に低レベルのマイクロ波放射が引き起こしたデオキシリボ核酸損傷と遺伝毒性との判別] med./bio.

Detection of Low Level Microwave Radiation Induced Deoxyribonucleic Acid Damage Vis-a-vis Genotoxicity in Brain of Fischer Rats.

掲載誌: Toxicol Int 2013; 20 (1): 19-24

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研究目的(著者による)

To examine the potential DNA damaging effects of microwave exposure in the brain of rats.

詳細情報

4 groups of rats were examined (n=6 per group): 1.) sham exposure, 2.) exposure to 900 MHz, 3.) exposure to 1800 MHz and 4.) exposure to 2450 MHz.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
ばく露時間: 2 h/day, 5 days/week for 30 days
  • SAR: 0.5953 mW/kg
ばく露2: 1,800 MHz
ばく露時間: 2 h/day, 5 days/week for 30 days
  • SAR: 0.5838 mW/kg
ばく露3: 2,450 MHz
ばく露時間: 2 h/day, 5 days/week for 30 days
  • SAR: 0.6672 mW/kg

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 2 h/day, 5 days/week for 30 days
ばく露装置
ばく露の発生源/構造
  • GTEMセル
Distance between exposed object and exposure source 1 m
チャンバの詳細 rats were restrained in a 30 cm Œ 5 cm Œ 20 cm (length x width x height) closed box divided into four compartments with holes of 1 cm diameter for ventilation, four rats per box, 2 boxes per exposure
ばく露装置の詳細 GTEM cell with outer dimensions of 220 cm x 120 cm x 80 cm (length x width x height); microwave chamber is lined with absorbers which minimize the possibility of any reflections; GTEM cell was placed in a temperature controlled room under constant lighting conditions
Sham exposure A sham exposure was conducted.
パラメータ
測定量 種別 Method Mass 備考
SAR 0.5953 mW/kg - 計算値 - -

ばく露2

主たる特性
周波数 1,800 MHz
タイプ
  • electromagnetic field
ばく露時間 2 h/day, 5 days/week for 30 days
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
SAR 0.5838 mW/kg - 計算値 - -

ばく露3

主たる特性
周波数 2,450 MHz
タイプ
  • electromagnetic field
ばく露時間 2 h/day, 5 days/week for 30 days
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
SAR 0.6672 mW/kg - 計算値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

In all exposure groups, a significant increase in DNA single-strand breaks was found in comparison to the control group.
The authors conclude that exposure to microwaves could have a DNA damaging effect in the brain of rats.

研究の種別:

研究助成

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