Study type: Medical/biological study (experimental study)

Effects of 2.4 GHz radiofrequency radiation emitted from Wi-Fi equipment on microRNA expression in brain tissue. med./bio.

Published in: Int J Radiat Biol 2015; 91 (7): 555-561

Aim of study (acc. to author)

The effects of a chronic exposure of rats to a 2.4 GHz electromagnetic field (WLAN) on the expression rates of some microRNAs in the brain should be investigated.

Background/further details

MicroRNAs are small, non-coding RNA molecules, which play an important role in growth, differentiation, proliferation and cell death by influencing the gene expression in cells.
Rats were divided in 2 groups (n=8 each): 1) exposure and 2) sham exposure.
All measurements were conducted in triplicates.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.4 GHz
Exposure duration: continuous for 24 hours/day for 12 months

Exposure 1

Main characteristics
Frequency 2.4 GHz
Type
Charakteristic
Exposure duration continuous for 24 hours/day for 12 months
Additional info WiFi or WLAN signal
Exposure setup
Exposure source
Distance between exposed object and exposure source 50 cm
Chamber plexiglass cage (55 x 32 x 20 cm)
Setup rats could move freely in cage; WLAN signal generator was connected to a tuned half-wavelength dipole antenna positioned in front of a reflector plate to direct the signal to the cage; a temperature of 22°C and a relative humidity of 45% were maintained; cage was surrounded with electromagnetic absorber material backed by metal to isolate outdoor electromagnetic fields
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power 100 mW peak value - - -
power 50 mW effective value - - -
SAR 4,000 µW/kg peak value calculated - -
SAR 1,510 µW/kg average over mass calculated 1 g -
SAR 1,030 µW/kg average over mass calculated 10 g -
SAR 141.4 µW/kg effective value calculated whole body -
SAR 7,127 µW/kg maximum calculated whole body -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The expression rates of rno-miR-106b-5p and rno-miR-107 were significantly decreased in the exposure group in comparison to the sham exposure group.
The authors conclude that a chronic exposure of rats to a 2.4 GHz electromagnetic field (WLAN) could influence the expression rates of some microRNAs in the brain with possibly adverse consequences for the brain.

Study character:

Study funded by

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