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The effects of a chronic exposure of rats to a 2.4 GHz electromagnetic field (WLAN) on the expression rates of some microRNAs in the brain should be investigated.
MicroRNAs are small, non-coding RNA molecules, which play an important role in growth, differentiation, proliferation and cell death by influencing the gene expression in cells.
Rats were divided in 2 groups (n=8 each): 1) exposure and 2) sham exposure.
All measurements were conducted in triplicates.
ばく露時間: continuous for 24 hours/day for 12 months
|Distance between exposed object and exposure source||50 cm|
|チャンバの詳細||plexiglass cage (55 x 32 x 20 cm)|
|ばく露装置の詳細||rats could move freely in cage; WLAN signal generator was connected to a tuned half-wavelength dipole antenna positioned in front of a reflector plate to direct the signal to the cage; a temperature of 22°C and a relative humidity of 45% were maintained; cage was surrounded with electromagnetic absorber material backed by metal to isolate outdoor electromagnetic fields|
|Sham exposure||A sham exposure was conducted.|
The expression rates of rno-miR-106b-5p and rno-miR-107 were significantly decreased in the exposure group in comparison to the sham exposure group.
The authors conclude that a chronic exposure of rats to a 2.4 GHz electromagnetic field (WLAN) could influence the expression rates of some microRNAs in the brain with possibly adverse consequences for the brain.