Study type: Medical/biological study (experimental study)

The effects of electromagnetic fields on the number of ovarian primordial follicles: An experimental study. med./bio.

Published in: Kaohsiung J Med Sci 2015; 31 (6): 287-292

Aim of study (acc. to author)

The effects of an abdominal exposure of rats to a 900 MHz electromagnetic field on the number of primordial follicles in the ovaries should be investigated.

Background/further details

Primordial follicles represent the primary state of ovarian follicles. They consist of an ovum and a layer of flattened epithelial cells.
Rats were randomly divided into two groups (n=8 each): 1) exposure to the electromagnetic field and 2) sham exposure.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 15 minutes/day for 15 days

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 15 minutes/day for 15 days
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
Exposure setup
Exposure source
Chamber radio frequency-shielded room
Setup the researcher's left hand grasped the rat at the neck and back and the right hand applied the antenna device to the skin of the rat over the ovaries in the lower abdominal area; ambient temperature of 22-26°C and 55-60% humidity
Sham exposure A sham exposure was conducted.
Additional info rats of the sham exposure group were taken from their cages and treated with the antenna in the same manner as rats in the experimental group, but the exposure device was turned off
Parameters
Measurand Value Type Method Mass Remarks
power 5 W peak value - - output power
power density 1.04 mW/cm² - measured - -
SAR 0.018 W/kg minimum measured whole body -
SAR 4 W/kg maximum measured whole body -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • after exposure

Main outcome of study (acc. to author)

No significant differences were found in the body weight and weight of ovaries between exposed and sham exposed rats.
The mean numbers of primordial follicles in the ovaries were significantly lower in exposed rats compared to sham exposed rats.
The authors conclude that an abdominal exposure of rats to a 900 MHz electromagnetic field could reduce the number of primordial follicles in the ovaries.

Study character:

Study funded by

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