Study type: Medical/biological study (experimental study)

1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice. med./bio.

Published in: Bioelectromagnetics 2016; 37 (6): 391-399

Aim of study (acc. to author)

The effects of exposure of Alzheimer's disease model mice to a 1950 MHz electromagnetic field on memory and the beta-amyloid protein metabolism should be investigated as parameters for Alzheimer's disease pathology.

Background/further details

Mice were divided into two groups (n=8 each): 1) exposure to the electromagnetic field and 2) sham exposure.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 1,950 MHz
Exposure duration: 2 h/day, 5 days/week for 3 months

Exposure 1

Main characteristics
Frequency 1,950 MHz
Type
Exposure duration 2 h/day, 5 days/week for 3 months
Modulation
Modulation type cf. additional info
Additional info

WCDMA format

Exposure setup
Exposure source
Chamber reverberation chamber of 2295 x 2293 x 470 mm3; walls were made of stainless steel with a thickness of 2.3 mm
Setup microprocessor created WCDMA formated signal; difference in field distribution in chamber was less than 3 dB
Sham exposure A sham exposure was conducted.
Additional info during exposure, air temperature in the test area inside was maintained at 20 ± 3°C; body temperature did not increase by more than 0.5°C (changes ranged from -1.9 to +0.5°C), and body temperature was thus maintained within the normal range
Parameters
Measurand Value Type Method Mass Remarks
power 52 W - - - output power
SAR 5 W/kg mean calculated whole body -

Reference articles

  • Lee HJ et al. (2012): The effects of simultaneous combined exposure to CDMA and WCDMA electromagnetic fields on rat testicular function.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No significant differences were found between exposed and sham-exposed mice in any parameter.
The authors conclude that exposure of Alzheimer's disease model mice to a 1950 MHz electromagnetic field has no effect on memory and the beta-amyloid protein metabolism, which were investigated as parameters for Alzheimer's disease pathology.

Study character:

Study funded by

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