Animals were individually confined in Perspex cages (14 x 5 x 5 cm) limiting their movement without explicit restraint. Three of the small cages were secured to a Perspex base plate which fitted closely within a container (34 x 20 x 12.5 cm) of twin wall, corrugated polypropylene.
The box was positioned centred along the mid-line of the cell so that the animals were placed mid-way between septum and floor which had a separation of 90 cm at this point.
Based on the SAR estimates, the absorbed energy per pulse had a range of 0.19 to 0.25 mJ/kg, with a mean of 0.23 mJ/kg.
Measurement and calculation details
The output voltage of the amplifier measured by means of a coaxial RF millivoltmeter was used by the control system to adjust the signal source output level to keep exposures within ± 0.6 V/m of the target. A field uniformity of better than ±10% across the volume occupied by the animals was confirmed by measurements made using a single axis probe utilising an electrically short dipole and diode detector and a 3-axis E-fieldprobe. The dominant field component was vertical. The whole-body SAR was estimated using data for a prolate spheroid model of a mouse in the K orientation.
No significant field-dependent effects on performance were found in choice accuracy or in total times to complete the task across the experiment. These data suggest that exposure to radiofrequencyradiation simulating a GSMsignal under the conditions of this experiment does not affect the acquisition of the learned response.
Son Y et al.
1950 MHz radiofrequency electromagnetic fields do not aggravate memory deficits in 5xFAD mice.
Narayanan SN et al.
Possible cause for altered spatial cognition of prepubescent rats exposed to chronic radiofrequency electromagnetic radiation.
Banaceur S et al.
Whole body exposure to 2.4 GHz WIFI signals: Effects on cognitive impairment in adult triple transgenic mouse models of Alzheimer's disease (3xTg-AD).
Ikinci A et al.
The Effects of Prenatal Exposure to a 900 Megahertz Electromagnetic Field on Hippocampus Morphology and Learning Behavior in Rat Pups.
Hao D et al.
Effects of long-term electromagnetic field exposure on spatial learning and memory in rats.
Lu Y et al.
Glucose administration attenuates spatial memory deficits induced by chronic low-power-density microwave exposure.
Dragicevic N et al.
Long-term electromagnetic field treatment enhances brain mitochondrial function of both Alzheimer's transgenic mice and normal mice: a mechanism for electromagnetic field-induced cognitive benefit?
Arendash GW et al.
Electromagnetic field treatment protects against and reverses cognitive impairment in Alzheimer's disease mice.