Triple transgenic mice with three human genes associated with Alzheimer's disease were used: Amyloid Beta Precursor protein (APP sw), Presenilin 1 (PS1M146V), and tau P301L. The non transgenic mice (wild type) had the same genetic backround as the transgenic mice.
Mice were divided into four groups (each group n = 7): two groups of transgenic mice (exposed and sham exposed), and two groups of wild type mice (exposed and sham exposed).
Exposure duration: continuous for 2 h/day on 28 days
|Exposure duration||continuous for 2 h/day on 28 days|
|SAR||1.6 W/kg||-||-||whole body||-|
The data demonstrated that radiofrequency exposure improved cognitive behavior of transgenic mice in the Dark/Light-Box test and the Barnes maze. Exposure to the WiFi signals reduced the latency and made the transgenic mice less anxious. No effects on locomotor activity, body weight or body temperature were found.
The authors conclude that radiofrequency exposure may represent an effective memory-enhancing approach in Alzheimer's disease.