Study type: Medical/biological study (experimental study)

The correlation between the frequency of micronuclei and specific chromosome aberrations in human lymphocytes exposed to microwave radiation in vitro med./bio.

By: Garaj-Vrhovac V, Fucic A, Horvat D
Published in: Mutation Research - Letters 1992; 281 (3): 181-186
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Aim of study (acc. to author)

1) To explain the origin of micronuclei with regard to specific chromosome aberrations (acentric fragments and dicentric chromosomes), and 2) to detect the genotoxic effect of microwave radiation by analysis of structural chromosome aberrations and the micronucleus test in human lymphocytes.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 7.7 GHz
Exposure duration: 10, 30 and 60 min.
  • power: 2 W (max output of the generator)
  • power density: 5 W/m² (10 mW/cm² and 30 mW/cm²)

Exposure 1

Main characteristics
Frequency 7.7 GHz
Type
Waveform
Exposure duration 10, 30 and 60 min.
Exposure setup
Exposure source
Setup samples placed below the horn antenna on a thin bakelite plate (1.2 m high).
Additional info for more details on exposure set-up pls see reference article.
Parameters
Measurand Value Type Method Mass Remarks
power 2 W - cf. remarks - max output of the generator
power density 5 W/m² - cf. remarks - 10 mW/cm² and 30 mW/cm²

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results indicate that microwave radiation causes changes in the genome of somatic human cells. A positive correlation between micronuclei and specific chromosomal aberrations after exposure was observed. In the exposed sampels the presence of dicentric and ring chromosomes was established.

Study character:

Study funded by

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