Study type: Medical/biological study (experimental study)

Effect of 900 MHz Electromagnetic Radiation on the Induction of ROS in Human Peripheral Blood Mononuclear Cells. med./bio.

Published in: J Biomed Phys Eng 2015; 5 (3): 105-114

Aim of study (acc. to author)

The effects of exposure of human blood samples to a 900 MHz electromagnetic field (GSM) on oxidative stress in monocytes and lymphocytes should be investigated.

Background/further details

Blood samples were obtained from 13 healthy volunteers. Each sample was divided and one half was assigned to an exposure group (group 1) and the other half to a control group (group 2). After exposure, enriched fractions of monocytes and lymphocytes were investigated, respectively.
A positive control was conducted.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 2 hours

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Waveform
Exposure duration continuous for 2 hours
Additional info signal bandwidth was 200 kHz
Modulation
Modulation type pulsed
Pulse width 463 µs
Duty cycle 12.5 %
Repetition frequency 217 Hz
Exposure setup
Exposure source
Chamber 6 well dishes
Setup the signal was generated by a GSM simulator and transferred to a rectangular waveguide made of aluminum by a co-axial wire; the samples were placed at a location with maximum electric and magnetic fields in the waveguide to provide a relatively homogeneous field for exposure; the increase of temperature was not more than 0.1°C
Parameters
Measurand Value Type Method Mass Remarks
power 2 W - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Monocytes in the exposure group (group 1) showed a significantly increased content of reactive oxygen species compared to the control group (group 2). No significant differences between both groups were found in lymphocytes.
The authors conclude that exposure of human blood samples to a 900 MHz electromagnetic field (GSM) might induce oxidative stress in monocytes, although the consequences for health are not clear.

Study character:

Study funded by

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