Study type: Medical/biological study (experimental study)

Effects of 2.45 GHz microwave exposures on the peroxidation status in Wistar rats. med./bio.

Published in: Niger Postgrad Med J 2003; 10 (4): 243-246

Aim of study (acc. to author)

To study the effect of microwave exposure on lipid peroxidation status in rats.

Background/further details

The effect of administration of the antioxidants ascorbic acid and alpha-tocopherol was also studied.
120 rats were divided into the following groups (each group = 5 rats): Six groups served as control group, six groups were microwave exposed, six groups were treated with ascorbic acid, and six groups were treated with alpha-tocopherol (both four days before exposure). The lipid peroxidation was monitored for a period of 8 weeks post irradiation.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: not given in the article

General information

For further information on the setup see also: Guy A. W, Dosimetry of Exposure to VLF to Microwaves, Health Physics. 1987; 56: 1 - 6.
Animals were divided into the following groups: i) microwave exposure ii) microwave exposure + 1 mg/kg ascorbic acid - 4 days before exposure iii) microwave exposure + 1 mg/kg alpha-tocopherol - 4 days before exposure iv) control

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration not given in the article
Exposure setup
Exposure source
Distance between exposed object and exposure source 12 cm
Chamber irradiation chamber surfaces lined with water
Parameters
Measurand Value Type Method Mass Remarks
power density 6 mW/cm² maximum measured - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The microwave exposure caused an increase in the lipid peroxidation within the first 24 hours after exposure, and then gradually reduced to the value of the control group after about one week. Ascorbic acid and alpha-tocopherol administration caused a decrease of the control value of the lipid peroxidation within the first week after irradiation.
The data demonstrated that microwave exposure caused significant increase in the lipid peroxidation status and there were protective effects of the antioxidants ascorbic acid and alpha-tocopherol.

Study character:

Study funded by

Related articles