Study type: Epidemiological study (observational study)

Pooled analysis of two case-control studies on use of cellular and cordless telephones and the risk for malignant brain tumours diagnosed in 1997-2003. epidem.

Published in: Int Arch Occup Environ Health 2006; 79 (8): 630-639

Aim of study (acc. to author)

A pooled analysis of two previous case-control studies on the use of cellular and cordless telephones and the risk of malignant brain tumors was conducted in Sweden.

Further details

The first case-control study regarding the period 1997-2000 was published in the publications 9520 and 9895, the second study regarding the period 2000-2003 in publications 12068 and 12259.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Exposure groups

Group Description
Reference group 1 unexposed
Group 2 analog, cumulative lifetime use: 1- 1,000 hours
Group 3 analog, cumulative lifetime use: 1,001 - 2,000 hours
Group 4 analog, cumulative lifetime use: > 2,000 hours
Group 5 digital, cumulative lifetime use: 1- 1,000 hours
Group 6 digital, cumulative lifetime use: 1,001 - 2,000 hours
Group 7 digital, cumulative lifetime use: > 2,000 hours
Group 8 cordless, cumulative lifetime use: 1- 1,000 hours
Group 9 cordless, cumulative lifetime use: 1,001 - 2,000 hours
Group 10 cordless, cumulative lifetime use: ≥ 2,000 hours
Group 11 analog > 1- to 5-year latency period
Group 12 analog > 5- to 10-year latency period
Group 13 analog > 10-year latency period
Group 14 analog total, > 1-year latency period
Group 15 analog ≤ 85 h, > 1- to 5-year latency period
Group 16 analog ≤ 85 h, > 5- to 10-year latency period
Group 17 analog ≤ 85 h, > 10-year latency period
Group 18 analog ≤ 85 h, total, > 1-year latency period
Group 19 analog > 85 h, > 1- to 5-year latency period
Group 20 analog > 85 h, > 5- to 10-year latency period
Group 21 analog > 85 h, > 10-year latency period
Group 22 analog > 85 h, total, > 1-year latency period
Group 23 digital > 1- to 5-year latency period
Group 24 digital > 5- to 10-year latency period
Group 25 digital > 10-year latency period
Group 26 digital total, > 1-year latency period
Group 27 digital ≤ 64 h, > 1- to 5-year latency period
Group 28 digital ≤ 64 h, > 5- to 10-year latency period
Group 29 digital ≤ 64 h, > 10-year latency period
Group 30 digital ≤ 64 h, total, > 1-year latency period
Group 31 digital > 64 h, > 1- to 5-year latency period
Group 32 digital > 64 h, > 5- to 10-year latency period
Group 33 digital > 64 h, > 10-year latency period
Group 34 digital > 64 h, total, > 1-year latency period
Group 35 cordless > 1- to 5-year latency period
Group 36 cordless > 5- to 10-year latency period
Group 37 cordless > 10-year latency period
Group 38 cordless total, > 1-year latency period
Group 39 cordless ≤ 195 h, > 1- to 5-year latency period
Group 40 cordless ≤ 195 h, > 5- to 10-year latency period
Group 41 cordless ≤ 195 h, > 10-year latency period
Group 42 cordless ≤ 195 h, total, > 1-year latency period
Group 43 cordless > 195 h, > 1- to 5-year latency period
Group 44 cordless > 195 h, > 5- to 10-year latency period
Group 45 cordless > 195 h, > 10-year latency period
Group 46 cordless > 195 h, total, > 1-year latency period

Population

Case group

Control group

Study size

Cases Controls
Eligible 1,008 2,437
Participants 905 2,162
Participation rate 90 % 89 %
Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

The pooled analysis showed that use of cellular telephones and cordless telephones for more than 10 years significantly increased the risk for malignant brain tumors. The risk increased with cumulative lifetime number of hours of use.

Study funded by

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