Study type: Medical/biological study (experimental study)

Expression of the immediate early gene, c-fos, in mouse brain after acute global system for mobile communication microwave exposure. med./bio.

Published in: Pathology 2005; 37 (3): 231-233

Aim of study (acc. to author)

To study the effect of acute exposure to GSM (Global System for Mobile Communication) radiofrequency fields on immediate early gene (c-fos) expression in the brain.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 60 min
  • SAR: 4 W/kg average over mass (whole body)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Charakteristic
Exposure duration continuous for 60 min
Modulation
Modulation type pulsed
Pulse width 0.6 ms
Repetition frequency 217 Hz
Exposure setup
Exposure source
Setup Exposure modules (with well-defined dosimetry) consisted of a cylindrical parallel plate with mice restrained in ventilated clear Perspex tubes arranged around the antenna.
Additional info Three groups of mice were used: exposed, sham-exposed and control mice without handling or further restraint.
Parameters
Measurand Value Type Method Mass Remarks
SAR 4 W/kg average over mass unspecified whole body -

Reference articles

  • Finnie JW et al. (2001): Effect of global system for mobile communication (gsm)-like radiofrequency fields on vascular permeability in mouse brain.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Activation of c-fos in the brains of exposed and sham-exposed mice was comparable, but it was greatly increased compared to brains of freely moving control animals. These data indicate that the majority of the acute genomic response detected by c-fos expression was due to immobilisation rather than irradiation.

Study character:

Study funded by

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