To study the effects of extremely low frequency magnetic field on cell proliferation, antioxidative enzyme activities and malondialdehyde concentration in preadipocyte (precursor cells of adipocytes (lipocytes)) cell culture.
Exposure duration: continuous for 36 min
|Exposure duration||continuous for 36 min|
|magnetic flux density||120 µT||unspecified||unspecified||-||-|
Extremely low frequency magnetic field exposure lasting 36 minutes daily failed to influence cell count after 24 h and 48 h of incubation.
After 24 h, in the magnetic field exposed group, manganese- and copper-zinc-containing superoxide dismutase enzyme activities were decreased, catalase activity was increased, whereas there were no significant differences in glutathione peroxidase and glutathione reductase activities in comparison to the control. After 48 h of incubation, all enzyme activities were reduced, except for glutathione reductase, in which no changes were found.
Malondialdehyde concentration at 24 h after incubation with the magnetic field exposure was significantly higher in comparison to the control. After 48 h of incubation, malondialdehyde levels were significantly lower in both groups (with no differences between the groups without and with magnetic field exposure).
The authors conclude that extremely low frequency magnetic field influences antioxidative enzyme activities and increases lipid peroxidation in these preadipocyte cultures.