Study type: Epidemiological study (observational study)

Mobile phone use and risk of glioma: a case-control study in Korea for 2002-2007. epidem.

Published in: Environ Health Toxicol 2015; 30: e2015015

Aim of study (acc. to author)

A case-control study was conducted in Korea to investigate the association between mobile phone use and the development of gliomas.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Exposure groups

Group Description
Reference group 1 mobile phone use: no
Group 2 mobile phone use: yes
Reference group 3 type of mobile phone: no
Group 4 type of mobile phone: analog
Group 5 type of mobile phone: analog and digital
Group 6 type of mobile phone: digital
Reference group 7 lifetime years of use: no use
Group 8 lifetime years of use: < 4 years
Group 9 lifetime years of use: 4 - 7 years
Group 10 lifetime years of use: > 7 years
Reference group 11 cumulative hours of use: no use
Group 12 cumulative hours of use: < 300 hours
Group 13 cumulative hours of use: 300 - 900 hours
Group 14 cumulative hours of use: > 900 hours
Reference group 15 monthly sevice fee: no use
Group 16 monthly sevice fee: < 30,000 Korean won
Group 17 monthly sevice fee: 30,000 - 49,000 Korean won
Group 18 monthly sevice fee: 50,000 - 80,000 Korean won
Group 19 monthly sevice fee: > 80,000 Korean won
Reference group 20 average daily receiving calls: no use
Group 21 average daily receiving calls: ≤ 2
Group 22 average daily receiving calls: 3 - 5
Group 23 average daily receiving calls: 6 - 9
Group 24 average daily receiving calls: ≥ 10
Reference group 25 average daily sending calls: no use
Group 26 average daily sending calls: ≤ 2
Group 27 average daily sending calls: 3 - 5
Group 28 average daily sending calls: 6 - 9
Group 29 average daily sending calls: ≥ 10
Reference group 30 average duration time: no use
Group 31 average duration time: ≤ 2 min
Group 32 average duration time: 3 - 4 min
Group 33 average duration time: ≥ 5 min
Reference group 34 mechanism: no use
Group 35 mechanism: flip-type
Group 36 mechanism: folder-type
Group 37 mechanism: sliding-type
Reference group 38 carriage: no use
Group 39 carriage: in bag
Group 40 carriage: hung by neck
Group 41 carriage: in shirt
Group 42 carriage: in pants
Group 43 carriage: at hand

Population

Case group

Control group

Study size

Cases Controls
Eligible 897 1,051
Evaluable 285 285
Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

Overall, no significant association was observed between gliomas and regular use of mobile phones and different types of exposure measures. For ipsilateral use, a statistically non-significant increase was found for lifetime years of use and cumulative hours of use (OR 1.25, CI 0.55-2.88 and OR 1.77, CI 0.32-1.84, respectively). However, the contralateral users showed slightly lower risk than ipsilateral users.
The authors conclude that results do not support the hypothesis that the use of mobile phones increases the risk of glioma.

Limitations (acc. to author)

Selection bias and recall bias cannot be excluded.

Study funded by

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