Study type: Medical/biological study (experimental study)

Effect of 50-Hz 1-mT magnetic field on the uterus and ovaries of rats (electron microscopy evaluation) med./bio.

Published in: Med Sci Monit 2006; 12 (6): BR215-BR220

Aim of study (acc. to author)

To study the effect of extremely low frequency magnetic fields on the uterus and ovary of rats.

Background/further details

48 rats were divided into two groups, one for 50 and the other for 100 days of exposure.



Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: repeated daily exposure, 3 h/day for 50 or 100 days

Exposure 1

Main characteristics
Frequency 50 Hz
Exposure duration repeated daily exposure, 3 h/day for 50 or 100 days
Exposure setup
Exposure source
Chamber The coils were placed face to face vertically and horizontally in a Faraday cage (130 x 65 x 80 cm)
Setup Animals were exposed in Plexiglass cages (32 x 18 x 15 cm). Animals for sham exposure were kept under the same condition but in the absence of magnetic field.
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT mean measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data showed that 50 and 100 days of exposure to a 1 mT extremely low frequency magnetic field can cause alterations at the cellular level and in malondialdehyde concentration.
Ultrastructural dissolution, decrease in cell organelles, cavities in cells, and typical structural loss of the nucleus were revealed in germinal epithelial cells of the ovaries in the 50-days exposure group. Ultrastructural alterations in germinal epithelium and tunica albuginea of ovaries, irregularity in nucleus and nucleolus, increase in lipid vacuoles of cell cytoplasm and reduction in organelles were found in ovaries in the 100-days exposure group. Similar alterations were observed in uterus.
Malondialdehyde concentration of the ovaries and uterus increased in rats of the two exposure groups.

Study character:

Study funded by

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