Study type: Medical/biological study (experimental study)

Comparison of the effect of ELF on total RNA content in normal and transformed human cells. med./bio.

Published in: Ann N Y Acad Sci 1992; 649: 353-355

Aim of study (acc. to author)

To study the effects of extremely low frequency electromagnetic fields on cellular transcription.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Modulation type: CW
Exposure duration: continuous for 30 min and 60 min
Exposure 2: 60 Hz
Modulation type: pulsed
Exposure duration: 30 min and 60 min

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Exposure duration continuous for 30 min and 60 min
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.1 mT - - - -

Exposure 2

Main characteristics
Frequency 60 Hz
Type
Exposure duration 30 min and 60 min
Modulation
Modulation type pulsed
Exposure setup
Exposure source
  • EBI generator
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.1 mT - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Total RNA increased for normal peripheral human lymphocytes and Daudi lymphoma cells that were exposed to pulsed electromagnetic fields. However, no effect on total RNA was seen in HL-60 cells exposed to pulsed electromagentic fields. The magnitude of the RNA fluorescence increase was greater in celles exposed to pulsed electromagnetic fields than in thoses exposed to 60 Hz.

Study character:

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