Study type: Medical/biological study (experimental study)

Evaluation of hematopoietic system effects after in vitro radiofrequency radiation exposure in rats med./bio.

Published in: Int J Radiat Biol 2011; 87 (2): 231-240

Aim of study (acc. to author)

To study the effect of a 900 MHz continuous wave radiofrequency exposure on the hematopoietic system in the rat.

Background/further details

Concanavalin A was used as positive control for proliferation rate test. Ultraviolet C radiation was used as positive control for the comet assay.
14 bones were used for bone marrow primary cell culture (either exposure or sham exposure) and 11 bones were used for lymphocytes primary cell culture (either exposure or sham exposure).



Exposure Parameters
Exposure 1: 900 MHz
Modulation type: CW
Exposure duration: continuous for 30 min

Exposure 1

Main characteristics
Frequency 900 MHz
Exposure duration continuous for 30 min
Modulation type CW
Exposure setup
Exposure source
Setup two petri dishes with bones, closed with parafilm and mounted on a 14 mm foam block, placed centrally in the TEM cell
Sham exposure A sham exposure was conducted.
Measurand Value Type Method Mass Remarks
power 16.7 W effective value - - -
SAR 2 W/kg mean calculated cf. remarks bone marrow

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data did not indicate any significant change in the proliferation rate of bone marrow cells and lymphocytes, erythrocyte maturation rate and DNA damage of lymphocytes.
In conclusion, these results did not reveal any effect on the hematopoietic system in rats for 900 MHz radiofrequency exposure (CW) at the 2 W/kg localised SAR limit value recommended by the International Commission on Non-Ionizing Radiation Protection for public exposures.

Study character:

Study funded by

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