Study type: Medical/biological study (experimental study)

One-year, simultaneous combined exposure of CDMA and WCDMA radiofrequency electromagnetic fields to rats med./bio.

Published in: Int J Radiat Biol 2011; 87 (4): 416-423

Aim of study (acc. to author)

To study whether one-year, long-term, simultaneous exposure to CDMA (849 MHz) and W-CDMA (1.95 GHz) radiofrequencies would induce chronic illness in rats.

Background/further details

The animals were divided into the following four groups (n=20/group): 1) male sham exposure group, 2) male combined radiofrequency exposure group, 3) female sham exposure group, and 4) female combined radiofrequency exposure group.



Exposure Parameters
Exposure 1: 849 MHz–1.95 GHz
Exposure duration: continuous for 45 min/day, 5 days/week for 12 months

General information

rats were treated in four groups: i) male sham exposure ii) male combined RF exposure iii) female sham exposure iv) female combined RF exposure

Exposure 1

Main characteristics
Frequency 849 MHz–1.95 GHz
Exposure duration continuous for 45 min/day, 5 days/week for 12 months
Additional info combined exposure to f = 849 MHz (CDMA) and f = 1.95 GHz (WCDMA)
Exposure setup
Exposure source
Chamber 2295 mm x 2293 mm x 1470 mm reverberation chamber with stainless walls; five cages placed in the exposure chamber; two rats placed in a 420 mm x 260 mm x 160 mm autoclaved polycarbonate cage; cage positions changed daily
Sham exposure A sham exposure was conducted.
Measurand Value Type Method Mass Remarks
SAR 2 W/kg - calculated - for CDMA and WCDMA each - resulting in 4 W/kg
power 30 W - measured - for CDMA
power 18 W - measured - for WCDMA

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

No animal died during the 12-month experimental period. No significant alterations in body and organ weights were observed under the simultaneous combined radiofrequency exposure. The data did not show any significant alterations based on urinalysis, haematology, blood biochemistry, or histopathology in most of the rats. The total tumour incidence was not different between sham exposed and exposed animals.
However, some altered parameters of the blood count and serum chemistry were found in radiofrequency exposed rats: The mean corpuscular haemoglobin in radiofrequency-exposed male rats was significantly increased compared with the sham exposed rats (however, no significant difference was observed in female rats). Additionally, the value of alkaline phosphatase was significantly increased only in radiofrequency exposed male rats and the values of total bilirubin and lactate dehydrogenase were decreased only in radiofrequency exposed female rats with statistical significance.
In conclusion, the data suggest that one-year chronic exposure to CDMA (849 MHz) and WCDMA (1.95 GHz) simultaneously did not increase chronic illness in rats, although there were some altered parameters in the blood count and serum chemistry.

Study character:

Study funded by

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